Endocrine Abstracts

Purpose: Diabetes is one of the most common metabolic disease which has got many peptide hormones have in its etiology. Phoenixin (PNX), a recently discovered neuropeptide appears to have a role in energy management and metabolism through regulating insulin neogenesis and secretion, according to research. There is no research has been studied on the association between diabetes and PNX levels. The aim of the study was to see if there was a relation between PNX levels in the se...

Introduction: Diabetes mellitus (DM) is a metabolic illness caused by insulin resistance or lack of it. Hypertension (HT) has been seen frequently in diabetic patients, and causes morbidity and mortality with its complications. Salusins are vasodilator and hypotensive peptids which function most in cardiovascular system. Apelin is an insulin-sensitive, vasoconstructive, positive inotropic-effective peptide. In this study, determining the levels of serum salusin-α, salusin...

Introduction: Diabetes mellitus is an important public health problem due to defects of the effect of the insulin or insulin deficiency, accompanied by chronic microvascular complications with diabetic nephropathy is characterised by proteinuria that the increasing number of patients progress to end stage renal disease. Many peptide hormone made in etiopathogenesis is situated, although adropin which discovered in recent years involves in glucose homeostasis, its relation to d...

Background/purpose: The combination of DM and HT accelerates vascular complications and increases the risk of mortality and morbidity. Hypertension is seen in half of diabetic patients. HT can be detected in approximately 40% of newly diagnosed diabetic patients. DM frequency increased 2.5 times in hypertensive patients. The association of HT and DM is due to the common mechanism responsible for the pathogenesis of both diseases. There is a limited number of studies investigat...